Acetic Acid → HCID 14405001, Verbindung
Reaktionsgleichung
[Cl:1][C:2]1[C:7]([F:8])=[CH:6][C:5]([F:9])=[C:4]([Cl:10])[C:3]=1[OH:11].C(O)(=O)C.[N+:16]([O-])([OH:18])=[O:17]>ClCCl>[Cl:1][C:2]1[C:7]([F:8])=[C:6]([N+:16]([O-:18])=[O:17])[C:5]([F:9])=[C:4]([Cl:10])[C:3]=1[OH:11]Komponenten
5
Edukt 3
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
20 g of 2,6-dichloro-3,5-difluorophenol are introduced into 70 ml of acetic acid, and 8 g of 98% strength nitric acid are added dropwise. The mixture is subsequently stirred for a further 2 hours at room temperature and taken up in 150 ml of dichloromethane, and the solution is washed twice with water. After removing the dichloromethane by distillation, 18 g of product remain. 94% purity according to GC analysis.
Aufarbeitung
- additionare added dropwise
- washthe solution is washed twice with water
- customAfter removing the dichloromethane
- distillationby distillation, 18 g of product
Quellen und Nachweise
- ORD-Eintrag
- ord-ea06658fa5aa4b67a80ea6d01647b260
- Quelldatensatz
- uspto-grants-1993_11
- Patentnummer
- US05260474
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