Thioacetamide → HCID 12369471, Verbindung
Reaktionsgleichung
[CH3:1][N:2]1[C:6]([N+:7]([O-:9])=[O:8])=[CH:5][N:4]=[C:3]1[C:10]#[N:11].C(N)(=[S:14])C>>[CH3:1][N:2]1[C:6]([N+:7]([O-:9])=[O:8])=[CH:5][N:4]=[C:3]1[C:10](=[S:14])[NH2:11]Komponenten
3
Versuchsvorschrift
1-methyl-5-nitro-2-cyanoimidazole (0.6mole) was dissolved in this mixture at 40° C. Thioacetamide (1.2 mole) was added and stirring continued for 3 hours at 40° C. The resultant solution was poured on to 4 liters of ice/water mixture and stirred for 30 minutes. The precipitate was collected, slurried with water, filtered and dried to yield 1-methyl-2-thiocarbamyl-5-nitroimidazole, m.p. 148°-50° C.
Aufarbeitung
- stirringstirred for 30 minutes
- customThe precipitate was collected
- filtrationfiltered
- customdried
Quellen und Nachweise
- ORD-Eintrag
- ord-7a3eac96a0bb45709544275ea30ca4b6
- Quelldatensatz
- uspto-grants-1977_07
- Patentnummer
- US04035390
Notizen zur Reaktion
Wird geladen…