Diethylcarbamoyl chloride → 1-Diethylcarbamoyl-3-diallylsulphamoyl-1,2,4-triazole

HRID 26116

Reaktionsgleichung

Reaktionsgleichung von HRID 26116
[CH2:1]([N:4]([CH2:13][CH:14]=[CH2:15])[S:5]([C:8]1[N:12]=[CH:11][NH:10][N:9]=1)(=[O:7])=[O:6])[CH:2]=[CH2:3].[CH2:16]([N:18]([CH2:22][CH3:23])[C:19](Cl)=[O:20])[CH3:17].C(N(CC)CC)C>O1CCCC1>[CH2:16]([N:18]([CH2:22][CH3:23])[C:19]([N:10]1[CH:11]=[N:12][C:8]([S:5](=[O:7])(=[O:6])[N:4]([CH2:1][CH:2]=[CH2:3])[CH2:13][CH:14]=[CH2:15])=[N:9]1)=[O:20])[CH3:17]

Komponenten

5

Edukt 3

HCID 6916Diethylcarbamoyl chlorideHCID 8471TriethylamineHCID 178457344HCID 178457344, Verbindung

Produkt 1

HCID 213242681-Diethylcarbamoyl-3-diallylsulphamoyl-1,2,4-triazole

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8028TetrahydrofuranLösungsmittel

Versuchsvorschrift

A mixture of 6.9 g. 3-diallylsulphamoyl-1,2,4-triazole, 4.5 g. diethylcarbamoyl chloride, 6ml. triethylamine and 25 ml. dry tetrahydrofuran was refluxed under anhydrous conditions for 1.5 hours. The cooled reaction mixture was filtered to remove triethylamine hydrochloride and the filtrate was evaporated to remove solvent. The solid residue was recrystallized from petroleum ether, b.p. 60°-80° C., to give 1-diethylcarbamoyl-3-diallylsulphamoyl-1,2,4-triazole, m.p. 49°-51° C. Elemental analysis satisfactory.

Aufarbeitung

  1. additionA mixture of 6.9 g
  2. customThe cooled reaction mixture
  3. filtrationwas filtered
  4. customto remove triethylamine hydrochloride
  5. customthe filtrate was evaporated
  6. customto remove solvent
  7. customThe solid residue was recrystallized from petroleum ether, b.p. 60°-80° C.

Quellen und Nachweise

ORD-Eintrag
ord-4267794288414405abf990af1d5262c8
Quelldatensatz
uspto-grants-1979_04
Patentnummer
US04148626

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