O-Xylene → N-Methylenepyrrolidonyl-2-Cyclopentoxyaniline

HRID 262014Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 262014
[CH:1]1([O:6][C:7]2[CH:13]=[CH:12][CH:11]=[CH:10][C:8]=2[NH2:9])[CH2:5][CH2:4][CH2:3][CH2:2]1.C([N:16]1[CH2:20][CH2:19][CH2:18][C:17]1=[O:21])O.[C:22]1(C)C(C)=CC=CC=1>O>[CH2:22]=[N:9][C:8]1[CH:10]=[CH:11][CH:12]=[C:13]([N:16]2[CH2:20][CH2:19][CH2:18][C:17]2=[O:21])[C:7]=1[O:6][CH:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1

Komponenten

5

Edukt 3

HCID 7237O-XyleneHCID 849112-Pyrrolidinone, 1-(hydroxymethyl)-HCID 64853982-(Cyclopentyloxy)aniline

Produkt 1

HCID 70609772N-Methylenepyrrolidonyl-2-CyclopentoxyanilineAusbeute 51,6 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

2-Cyclopentoxyaniline (10.0 g, 0.057 mole), N-methylolpyrrolidone (9.75 g, 0.85 mole) and xylene (25 cc) were refluxed under azeotropic conditions with the removal of 1.5 cc of water. The xylene was removed by rotary evaporation and the product was crystallized from 100 cc of hexane to yield 8.0 g (51.6%) of product, m.p. 87°-87.5° C.

Aufarbeitung

  1. customThe xylene was removed by rotary evaporation
  2. customthe product was crystallized from 100 cc of hexane

Quellen und Nachweise

ORD-Eintrag
ord-620428e63c7243ba8d19feeb5620722f
Quelldatensatz
uspto-grants-1979_05
Patentnummer
US04153446

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