2,6-Dimethylbenzaldehyde → HCID 178424784, Verbindung

HRID 262771

Reaktionsgleichung

Reaktionsgleichung von HRID 262771
[IH:1].[NH2:2][NH:3][C:4]([NH:6][CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][N:9]=1)=[NH:5].[CH3:14][C:15]1[CH:22]=[CH:21][CH:20]=[C:19]([CH3:23])[C:16]=1[CH:17]=O>C(O)(=O)C>[IH:1].[CH3:14][C:15]1[CH:22]=[CH:21][CH:20]=[C:19]([CH3:23])[C:16]=1[CH:17]=[N:2][NH:3][C:4]([NH:6][CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][N:9]=1)=[NH:5]

Komponenten

4

Edukt 2

HCID 5838412,6-DimethylbenzaldehydeHCID 178506604HCID 178506604, Verbindung

Produkt 1

HCID 178424784HCID 178424784, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 176Acetic AcidLösungsmittel

Versuchsvorschrift

A mixture of 2.93 g. of 1-amino-3-(2-pyridylmethyl)guanidine hydriodide and 1.34 g. of 2,6-dimethylbenzaldehyde [G. Lock and K. Schmidt, J. Prakt. Chem., 140, 229 (1934)] is dissolved in 5 ml. of glacial acetic acid at 100° C. After 2 hours the solidified reaction is triturated with water and filtered. Crystallization from absolute ethanol gives the desired product as colorless needles, m.p. 184°-186° C.

Aufarbeitung

  1. additionA mixture of 2.93 g
  2. customat 100° C
  3. customAfter 2 hours the solidified reaction
  4. customis triturated with water
  5. filtrationfiltered
  6. customCrystallization from absolute ethanol

Quellen und Nachweise

ORD-Eintrag
ord-b1081f16d9284e2eb077ef9734bdde77
Quelldatensatz
uspto-grants-1979_05
Patentnummer
US04154947

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