Potassium Carbonate → HCID 54199046, Verbindung

HRID 263028

Reaktionsgleichung

Reaktionsgleichung von HRID 263028
C(=O)([O-])[O-].[K+].[K+].[P:7](Cl)([O:11][CH3:12])([O:9][CH3:10])=[S:8].[C:14]([C:16]1[S:17][C:18]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)=[CH:19][C:20]=1[OH:21])#[N:15]>CC(C)=O>[C:14]([C:16]1[S:17][C:18]([C:22]2[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=2)=[CH:19][C:20]=1[O:21][P:7]([O:11][CH3:12])([O:9][CH3:10])=[S:8])#[N:15]

Komponenten

5

Edukt 3

HCID 11430Potassium CarbonateHCID 17304Dimethyl phosphorochloridothionateHCID 21317938HCID 21317938, Verbindung

Produkt 1

HCID 54199046HCID 54199046, VerbindungAusbeute 79 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 180AcetoneLösungsmittel

Reaktionsbedingungen

Temperatur
20 °C

Versuchsvorschrift

7 g of potassium carbonate and 8 g of O,O-dimethyl chlorothiophosphate were added to a solution of 10.5 g of 2-cyano-3-hydroxy-5-phenyl-thiophene in 120 ml of acetone and the mixture was stirred at 20° C. for 15 hours and was then filtered. The filtrate was evaporated to dryness and the crystal residue was empasted with petroleum ether. The crystals were then crystallized from isopropyl ether to obtain 12.8 g of 2-cyano-3-(dimethoxythiophosphoryloxy)-5-phenylthiophene melting at 95° C.

Aufarbeitung

  1. filtrationwas then filtered
  2. customThe filtrate was evaporated to dryness
  3. customThe crystals were then crystallized from isopropyl ether

Quellen und Nachweise

ORD-Eintrag
ord-6fe98b1acfe84105b8a74768c904c7d5
Quelldatensatz
uspto-grants-1979_05
Patentnummer
US04155996

Verknüpfte Notizen

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