HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Sodium hydride → 1-(7-Ethoxycarbonyl-heptyl)-2-methyl-4,5-diphenylimidazole
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Sodium hydride | HCID 24758 | — |
| Edukt | 4,5-Diphenyl-2-methylimidazole | HCID 236696 | — |
| Edukt | Ethyl 8-bromooctanoate | HCID 264813 | — |
| Produkt | 1-(7-Ethoxycarbonyl-heptyl)-2-methyl-4,5-diphenylimidazole | HCID 22916354 | 72,1% |
Reaktionsschritte
2-Methyl-4,5-diphenylimidazole (2.5 g) (J. Org. Chem., 1937, 2, 328) was reacted with sodium hydride (0.62 g) and ethyl 8-bromooctanoate (3.36 g) in a method similar to Example 12. Chromatography on silica gel eluted with a dichloromethane:ethanol gradient gave 1-(7-ethoxycarbonyl-heptyl)-2-methyl-4,5-diphenylimidazole (3.1 g, 72.1%) as an oil.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05648373 |
| Quelldatensatz | uspto-grants-1997_07 |
| ORD ID | ord-58bbdeb4d9a2409aaa20762d0339742c |
| Quellennotiz | uspto-grants-1997_07 |