Ethylamine → Benzenamine, 4-chloro-N-ethyl-2-nitro-

HRID 26705

Reaktionsgleichung

Reaktionsgleichung von HRID 26705
Cl[C:2]1[CH:7]=[CH:6][C:5]([Cl:8])=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10].[CH2:12]([NH2:14])[CH3:13]>C(O)C>[CH2:12]([NH:14][C:2]1[CH:7]=[CH:6][C:5]([Cl:8])=[CH:4][C:3]=1[N+:9]([O-:11])=[O:10])[CH3:13]

Komponenten

4

Edukt 2

HCID 6341Ethylamine2×HCID 69772,5-Dichloronitrobenzene

Produkt 1

HCID 97006Benzenamine, 4-chloro-N-ethyl-2-nitro-Ausbeute 89 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

A mixture of 26 g of 2,5-dichloro-nitrobenzene, 400 ml of ethanol and 25 ml of ethylamine was refluxed for 24 hours while adding 5 ml of ethylamine at 6 hour intervals and the mixture was cooled and filtered. The orange needles were washed with a small amount of an ethanol-ether mixture and dried over P2O5 under vacuum to obtain 24.4 g (89% yield) of N-ethyl-4-chloro-2-nitro-aniline melting at 90°-91° C.

Aufarbeitung

  1. temperaturewas refluxed for 24 hours
  2. temperaturethe mixture was cooled
  3. filtrationfiltered
  4. washThe orange needles were washed with a small amount of an ethanol-ether mixture
  5. dry with materialdried over P2O5 under vacuum

Quellen und Nachweise

ORD-Eintrag
ord-b590f27dd45e4daebcaa150698debc92
Quelldatensatz
uspto-grants-1979_04
Patentnummer
US04151280

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