N2 (benzyloxycarbonyl)-N1-isopentyl-L-prolinamide → HCID 57053150, Verbindung

HRID 267102Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 267102
N#N.C(OC([C@@:13]1([C:23]([NH2:25])=[O:24])[CH2:17][CH2:16][CH2:15][N:14]1[CH2:18][CH2:19][CH:20]([CH3:22])[CH3:21])=O)C1C=CC=CC=1>C(O)C.[Pd]>[CH2:18]([N:14]1[CH2:15][CH2:16][CH2:17][C@H:13]1[C:23]([NH2:25])=[O:24])[CH2:19][CH:20]([CH3:22])[CH3:21]

Komponenten

4

Edukt 1

HCID 86746219N2 (benzyloxycarbonyl)-N1-isopentyl-L-prolinamide

Produkt 1

HCID 57053150HCID 57053150, VerbindungAusbeute 111,5 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

A solution of 5.73 g of N2 -(benzyloxycarbonyl)-N1 -isopentyl-L-prolinamide in 600 ml of ethanol was hydrogenated over 0.8 g of 10% palladium-on-carbon catalyst for 3.75 hours. The catalyst was removed by filtration and the filtrate was evaporated to give 3.4 g of N1 -isopentyl-L-prolinamide as an oil which was used without further purification.

Aufarbeitung

  1. customThe catalyst was removed by filtration
  2. customthe filtrate was evaporated

Quellen und Nachweise

ORD-Eintrag
ord-43661b1651e143778e9b71bf14d20eb2
Quelldatensatz
uspto-grants-1997_07
Patentnummer
US05652369

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