4-Hydroxybenzoic Acid → Benzoic acid, 4-(acetyloxy)-

HRID 26719

Reaktionsgleichung

Reaktionsgleichung von HRID 26719
[OH:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][CH:3]=1.[C:11](Cl)(=[O:13])[CH3:12]>C1C=CC=CC=1>[C:11]([O:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][CH:3]=1)(=[O:13])[CH3:12]

Komponenten

4

Edukt 2

HCID 1354-Hydroxybenzoic AcidHCID 6367Acetyl chloride

Produkt 1

HCID 16865Benzoic acid, 4-(acetyloxy)-

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 241BenzeneLösungsmittel

Versuchsvorschrift

A solution of 20 g. of 4-hydroxybenzoic acid in 200 ml. of benzene and 40 ml. of acetyl chloride is refluxed for 3 hours. Solvent and excess acetyl chloride are evaporated. The mixture is dissolved in methanol (150 ml.) and water (20 ml.) added; after 15 minutes, addition of more water results in the precipitation of 4-acetoxy benzoic acid, m.p. 192°-193° C.

Aufarbeitung

  1. customSolvent and excess acetyl chloride are evaporated
  2. dissolutionThe mixture is dissolved in methanol (150 ml.)
  3. additionwater (20 ml.) added
  4. additionaddition of more water

Quellen und Nachweise

ORD-Eintrag
ord-97e6103d3157480888b34d018a955edc
Quelldatensatz
uspto-grants-1979_04
Patentnummer
US04151297

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