Reaktionsgleichung
[CH2:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][C:2]1=[O:10].[BH4-].[Na+]>CO>[CH2:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH:2]1[OH:10]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Reaktionsbedingungen
- Temperatur
- 40 °C
Versuchsvorschrift
A 60 g sample of 2-indanone (0.45 moles) in 1.5 liters of 40% aqueous methanol was treated with 18 g (0.46 moles) of sodium borohydride in portions with cooling to maintain T≤ 40°C. After the addition was complete (15 min), the mixture was stirred for 2 hrs then allowed to stand overnight at room temp. Ether extraction, drying over potassium carbonate and evaporation gave 58.3 g crystalline 2-indanol (96%).
Aufarbeitung
- temperaturewith cooling
- additionAfter the addition
- custom(15 min)
- waitto stand overnight at room temp
- extractionEther extraction
- dry with materialdrying over potassium carbonate and evaporation
Quellen und Nachweise
- ORD-Eintrag
- ord-6c8acacc781249eebb82cb28dffc8a49
- Quelldatensatz
- uspto-grants-1976_03
- Patentnummer
- US03943149
Verknüpfte Notizen
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