Acetyl chloride → Phenyl acetate

HRID 268510

Reaktionsgleichung

Reaktionsgleichung von HRID 268510
[O-:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:8](Cl)(=[O:10])[CH3:9]>CCOCC>[C:8]([O:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)(=[O:10])[CH3:9]

Komponenten

4

Edukt 2

HCID 6367Acetyl chlorideHCID 119047Phenolate

Produkt 1

HCID 31229Phenyl acetate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel2×

Versuchsvorschrift

A vigorously stirred suspension of thallous phenoxide (5 g., 0.017 m.) in anhydrous ether (15 ml.) is treated dropwise with freshly distilled acetyl chloride (1.33 g., 0.017 m.) in anhydrous ether (3 ml.) over 5 mins. at such a rate that the exothermic reaction is controlled. The mixture is then stirred for 1 hour at room temperature, the precipitated thallous chloride removed by filtration through Celite and the solvent evaporated under vacuum. The residual colorless oil is distilled to give phenyl acetate, 2.27 g., 98%, b.p. 110°/58 mm.

Aufarbeitung

  1. customat such a rate that the exothermic reaction
  2. customthe precipitated thallous chloride
  3. customremoved by filtration through Celite
  4. customthe solvent evaporated under vacuum
  5. distillationThe residual colorless oil is distilled

Quellen und Nachweise

ORD-Eintrag
ord-52748cb56aef414f9320e2f419e3bd4b
Quelldatensatz
uspto-grants-1976_03
Patentnummer
US03947488

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