Zurück
HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 269804Erstellt: 25. Oktober 2026

2-Fluoro-4-nitrotoluene → 2-(4-Amino-2-fluorophenyl)ethanol

https://huagongshe.com/reaction/269804

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt2-Fluoro-4-nitrotolueneHCID 74025—
EduktSodium MethoxideHCID 10942334—
LösungsmittelDimethyl SulfoxideHCID 679—
Produkt2-(4-Amino-2-fluorophenyl)ethanolHCID 45090600—

Reaktionsschritte

2-Fluoro-4-nitrotoluene and p-formaldehyde were allowed to undergo the reaction in DMSO in the presence of sodium methoxide, and then the resulting compound was subjected to catalytic hydrogenation in the same manner as shown in Reference Example 3 to obtain 3-fluoro-4-(2-hydroxyethyl)aniline. F: 156.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07449456B2
Quelldatensatzuspto-grants-2008_11
ORD IDord-a0076cd7d98346488810ae7fab1d0183
Quellennotizuspto-grants-2008_11