HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Fluoro-4-nitrotoluene → 2-(4-Amino-2-fluorophenyl)ethanol
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Fluoro-4-nitrotoluene | HCID 74025 | — |
| Edukt | Sodium Methoxide | HCID 10942334 | — |
| Lösungsmittel | Dimethyl Sulfoxide | HCID 679 | — |
| Produkt | 2-(4-Amino-2-fluorophenyl)ethanol | HCID 45090600 | — |
Reaktionsschritte
2-Fluoro-4-nitrotoluene and p-formaldehyde were allowed to undergo the reaction in DMSO in the presence of sodium methoxide, and then the resulting compound was subjected to catalytic hydrogenation in the same manner as shown in Reference Example 3 to obtain 3-fluoro-4-(2-hydroxyethyl)aniline. F: 156.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07449456B2 |
| Quelldatensatz | uspto-grants-2008_11 |
| ORD ID | ord-a0076cd7d98346488810ae7fab1d0183 |
| Quellennotiz | uspto-grants-2008_11 |