3,4-Dimethoxy-5-nitrobenzophenone → 3,4-Dihydroxy-5-nitrobenzophenone

HRID 274442Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 274442
C[O:2][C:3]1[CH:4]=[C:5]([CH:14]=[C:15]([N+:19]([O-:21])=[O:20])[C:16]=1[O:17]C)[C:6]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)=[O:7]>C(O)(=O)C.Br>[OH:2][C:3]1[CH:4]=[C:5]([CH:14]=[C:15]([N+:19]([O-:21])=[O:20])[C:16]=1[OH:17])[C:6]([C:8]1[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=1)=[O:7]

Komponenten

4

Edukt 1

HCID 214590553,4-Dimethoxy-5-nitrobenzophenone

Produkt 1

HCID 57479693,4-Dihydroxy-5-nitrobenzophenone

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 176Acetic AcidLösungsmittelHCID 260Hydrogen BromideLösungsmittel

Versuchsvorschrift

0.5 g of 3,4-dimethoxy-5-nitrobenzophenone is stirred at 110° for 30 hours in a mixture of 4 ml of acetic acid and 4 ml of 48 percent aqueous hydrobromic acid. The reaction mixture is subsequently evaporated to dryness. The residue is taken up in methylene chloride. It is washed with water, dried over sodium sulfate and evaporated. After recrystallization from methylene chloride/hexane there is obtained 3,4-dihydroxy-5-nitrobenzophenone of m.p. 132°.

Aufarbeitung

  1. customThe reaction mixture is subsequently evaporated to dryness
  2. washIt is washed with water
  3. dry with materialdried over sodium sulfate
  4. customevaporated
  5. customAfter recrystallization from methylene chloride/hexane there

Quellen und Nachweise

ORD-Eintrag
ord-37df08a5c8e54831b971f5968657e721
Quelldatensatz
uspto-grants-1995_02
Patentnummer
US05389653

Notizen zur Reaktion

Wird geladen…