Water → 2,2-Dimethyl-3-phenylpropanoic acid

HRID 274821Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 274821
[CH3:1][C:2]([CH3:15])([CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:3]([O:5]CC)=[O:4].[OH-].[K+].O>CO>[CH3:1][C:2]([CH3:15])([CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:3]([OH:5])=[O:4]

Komponenten

5

Edukt 3

HCID 962WaterHCID 14797Potassium HydroxideHCID 4684633Ethyl 2,2-dimethyl-3-phenylpropanoate

Produkt 1

HCID 218802,2-Dimethyl-3-phenylpropanoic acid

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

A solution of 1 g (20 mmol) of ethyl 2,2-dimethyl-3-phenylpropionate (stage 1) and 3.5 g (61 mmol) of potassium hydroxide in 15 ml of methanol was heated under reflux for 2 hours. Thereafter, 50 ml of water were added and the mixture was extracted twice with ether. The aqueous phase was acidified with concentrated hydrochloric acid and extracted again with ether, the organic phase was dried over magnesium sulfate and the solvent was striped off in vacuo.

Aufarbeitung

  1. temperatureunder reflux for 2 hours
  2. extractionthe mixture was extracted twice with ether
  3. extractionextracted again with ether
  4. dry with materialthe organic phase was dried over magnesium sulfate

Quellen und Nachweise

ORD-Eintrag
ord-efca2393aca843ff81caf973a753a5b9
Quelldatensatz
uspto-grants-1995_02
Patentnummer
USRE034865

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