6-Nitro-o-anisidine → 3-Methoxybenzene-1,2-diamine

HRID 275787

Reaktionsgleichung

Reaktionsgleichung von HRID 275787
[NH2:1][C:2]1[C:7]([N+:8]([O-])=O)=[CH:6][CH:5]=[CH:4][C:3]=1[O:11][CH3:12]>C(OCC)(=O)C.[Pd]>[NH2:1][C:2]1[C:7]([NH2:8])=[CH:6][CH:5]=[CH:4][C:3]=1[O:11][CH3:12]

Komponenten

4

Edukt 1

HCID 854916-Nitro-o-anisidine

Produkt 1

HCID 1842683-Methoxybenzene-1,2-diamineAusbeute 101,9 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 8857Ethyl AcetateLösungsmittel

Versuchsvorschrift

2-Amino-3-nitroanisole (4.3 g) was hydrogenated in ethyl acetate (200 ml) using catalytic 10% palladium on charcoal under an atmosphere of hydrogen at ambient temperature. Once complete the reaction mixture was filtered through Celite and the filtrate evaporated in vacuo to afford the title compound as a brown liquid (3.60 g).

Aufarbeitung

  1. customat ambient temperature
  2. filtrationwas filtered through Celite
  3. customthe filtrate evaporated in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-1931361c855c4e49b5bf142cad92b2bd
Quelldatensatz
uspto-grants-2002_03
Patentnummer
US06353010B1

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