1-Naphthylamine → HCID 12295945, Verbindung

HRID 278026Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 278026
[N:1]#[C:2]Br.[NH2:4][C:5]1[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[CH:8]=[CH:7][CH:6]=1>C1(C)C=CC=CC=1>[C:5]1([NH:4][C:2]#[N:1])[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[CH:8]=[CH:7][CH:6]=1

Komponenten

4

Edukt 2

HCID 86401-NaphthylamineHCID 10476Cyanogen Bromide

Produkt 1

HCID 12295945HCID 12295945, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel

Versuchsvorschrift

Cyanogen bromide (4.4 gm, 41.9 mmol) was added in portions to the stirred and ice-bath cooled solution of 1-aminonaphthalene (10.0 gm, 69.8 mmol) in toluene (100 mL). After 0.5 hour, the cooling bath was removed the reaction mixture was stirred at room temperature for 12 hours. The precipitate was filtered and the solid was triturated with water (150 mL) for 0.5 hour. The resulted solid was filtered and washed with water (4×20 mL) and the solid was dried in vacuum oven at 40° C. This material (4.6 gm) was used as such without any further purification.

Aufarbeitung

  1. customthe cooling bath was removed the reaction mixture
  2. stirringwas stirred at room temperature for 12 hours
  3. filtrationThe precipitate was filtered
  4. customthe solid was triturated with water (150 mL) for 0.5 hour
  5. filtrationThe resulted solid was filtered
  6. washwashed with water (4×20 mL)
  7. customthe solid was dried in vacuum oven at 40° C
  8. customsuch without any further purification

Quellen und Nachweise

ORD-Eintrag
ord-d4901e41c2b2428b94ea0144e652eff6
Quelldatensatz
uspto-grants-2002_03
Patentnummer
US06358993B1

Notizen zur Reaktion

Wird geladen…