3-(Trifluoromethyl)aniline → 3-oxo-N-[3-(trifluoromethyl)phenyl]butanamide
Reaktionsgleichung
[F:1][C:2]([F:11])([F:10])[C:3]1[CH:4]=[C:5]([CH:7]=[CH:8][CH:9]=1)[NH2:6].[CH2:12]=[C:13]1[O:17][C:15](=[O:16])[CH2:14]1>C1C=CC=CC=1>[F:1][C:2]([F:10])([F:11])[C:3]1[CH:4]=[C:5]([CH:7]=[CH:8][CH:9]=1)[NH:6][C:15](=[O:16])[CH2:14][C:13]([CH3:12])=[O:17]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
m-Trifluoromethyl aniline (32.22 g) in benzene was dissolved in benzene and diketene added slowly with mixing. The reaction mixture was allowed to stand at 25° C. The resulting solid product was recrystallized from ethanol to yield 3'-trifluoromethyl acetoacetanilide.
Aufarbeitung
- additionwith mixing
- customto stand at 25° C
- customThe resulting solid product was recrystallized from ethanol
Quellen und Nachweise
- ORD-Eintrag
- ord-e2e79f9094af4c188695b3e1de86223b
- Quelldatensatz
- uspto-grants-1980_09
- Patentnummer
- US04224334
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