Potassium Carbonate → 4-(4-Chloro-2-fluoroanilino)-6-methoxy-7-((2-methyl-4-pyridyl)methoxy)quinazoline

Reaktionsgleichung

S(Cl)(Cl)=O.[OH:5][CH2:6][C:7]1[CH:12]=[CH:11][N:10]=[C:9]([CH3:13])[CH:8]=1.[Cl:14][C:15]1[CH:34]=[CH:33][C:18]([NH:19][C:20]2[C:29]3[C:24](=[CH:25][C:26](O)=[C:27]([O:30][CH3:31])[CH:28]=3)[N:23]=[CH:22][N:21]=2)=[C:17]([F:35])[CH:16]=1.C(=O)([O-])[O-].[K+].[K+]>C1(C)C=CC=CC=1.CN(C=O)C.O>[Cl:14][C:15]1[CH:34]=[CH:33][C:18]([NH:19][C:20]2[C:29]3[C:24](=[CH:25][C:26]([O:5][CH2:6][C:7]4[CH:12]=[CH:11][N:10]=[C:9]([CH3:13])[CH:8]=4)=[C:27]([O:30][CH3:31])[CH:28]=3)[N:23]=[CH:22][N:21]=2)=[C:17]([F:35])[CH:16]=1