2-Chloro-4-nitropyridine 1-oxide → Pyridine, 2-chloro-4-methoxy-, 1-oxide

HRID 279834

Reaktionsgleichung

Reaktionsgleichung von HRID 279834
[Na].[CH3:2][O-:3].[Na+].[Cl:5][C:6]1[CH:11]=[C:10]([N+]([O-])=O)[CH:9]=[CH:8][N+:7]=1[O-:15]>CO>[Cl:5][C:6]1[CH:11]=[C:10]([O:3][CH3:2])[CH:9]=[CH:8][N+:7]=1[O-:15]

Komponenten

5

Edukt 3

HCID 844332-Chloro-4-nitropyridine 1-oxideHCID 5360545SodiumHCID 10942334Sodium Methoxide

Produkt 1

HCID 15593755Pyridine, 2-chloro-4-methoxy-, 1-oxide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel2×

Versuchsvorschrift

Sodium (0.46 g) is dissolved in absolute methanol (50 ml) and the resultant solution of sodium methoxide is added to a solution of 2-chloro-4-nitropyridine-1-oxide (3.5 g, prepared as described in Example 1) in methanol (10 ml). The reaction mixture is allowed to stand at room temperature for 50 hours and is then subjected to rotary evaporation to give 2-chloro-4-methoxypyridine-1-oxide.

Aufarbeitung

  1. customis then subjected to rotary evaporation

Quellen und Nachweise

ORD-Eintrag
ord-20c5b2c1ecd64b7c88f1f08ccc54e6e7
Quelldatensatz
uspto-grants-1986_05
Patentnummer
US04587240

Verknüpfte Notizen

Wird geladen…