4-Chlorobenzohydrazide → HCID 178465662, Verbindung

HRID 29807

Reaktionsgleichung

Reaktionsgleichung von HRID 29807
C[O-].[Na+].Cl.[C:5]([NH2:8])(=[NH:7])[CH3:6].[Cl:9][C:10]1[CH:19]=[CH:18][C:13]([C:14]([NH:16]N)=[O:15])=[CH:12][CH:11]=1>C(O)C>[NH:7]=[C:5]([NH:8][NH:16][C:14](=[O:15])[C:13]1[CH:18]=[CH:19][C:10]([Cl:9])=[CH:11][CH:12]=1)[CH3:6]

Komponenten

5

Edukt 3

HCID 108164-ChlorobenzohydrazideHCID 67170Acetamidine monohydrochlorideHCID 10942334Sodium Methoxide

Produkt 1

HCID 178465662HCID 178465662, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel2×

Versuchsvorschrift

1.09 g (20 mmol) sodium methoxide in 20 mL ethanol are added to a solution of 1.91 g (20 mmol) acetamidine hydrochloride in 30 mL ethanol. The mixture is stirred for 30 minutes at ambient temperature and then filtered. The filtrate is combined with 2.3 g (13.5 mmol) 4-chlorobenzoic acid hydrazide, stirred overnight at ambient temperature, cooled with an ice bath and then filtered. The precipitate is washed with cold ethanol and dried. Yellow solid. Yield: 1.45 g (51%); mass spectroscopy [M+H]+=212/214.

Aufarbeitung

  1. filtrationfiltered
  2. stirringstirred overnight at ambient temperature
  3. temperaturecooled with an ice bath
  4. filtrationfiltered
  5. washThe precipitate is washed with cold ethanol
  6. customdried

Quellen und Nachweise

ORD-Eintrag
ord-496ee62380ad4f8f9002a4d76b272e6b
Quelldatensatz
uspto-grants-2008_09
Patentnummer
US07423036B2

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