2-Bromo-5-methoxybenzoic acid → 2-(4-Chlorobenzoyl)-5-methoxybenzoic acid

HRID 29986

Reaktionsgleichung

Reaktionsgleichung von HRID 29986
Br[C:2]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].C([Li])CCC.[Cl:18][C:19]1[CH:30]=[CH:29][C:22]([C:23](N(OC)C)=[O:24])=[CH:21][CH:20]=1>>[Cl:18][C:19]1[CH:30]=[CH:29][C:22]([C:23]([C:2]2[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[CH:7][C:3]=2[C:4]([OH:6])=[O:5])=[O:24])=[CH:21][CH:20]=1

Komponenten

4

Edukt 3

HCID 899062-Bromo-5-methoxybenzoic acidHCID 112756634-Chloro-N-methoxy-N-methylbenzamideHCID 178418339Butyllithium

Produkt 1

HCID 692132772-(4-Chlorobenzoyl)-5-methoxybenzoic acid

Versuchsvorschrift

This compound is synthesized according to the method described in 3.2. by reacting 2-bromo-5-methoxybenzoic acid pretreated with n-butyllithium with 4-chloro-N-methoxy-N-methylbenzamide. It is used in crude form in the following reaction.

Aufarbeitung

  1. customThis compound is synthesized
  2. customin the following reaction

Quellen und Nachweise

ORD-Eintrag
ord-d55504ac77cd4e53af8c9e2bb4deec01
Quelldatensatz
uspto-grants-2008_09
Patentnummer
US07423030B2

Verknüpfte Notizen

Wird geladen…