Dimethyl Sulfoxide → 6-chloro-5-[2,6-difluoro-4-[3-(methylamino)propoxy]phenyl]-2-pyrazin-2-yl-N-(1,1,1-trifluoropropan-2-yl)pyrimidin-4-amine
Reaktionsgleichung
[CH3:30][NH:31][CH2:32][CH2:33][CH2:34][OH:35].[CH3:38][S:39]([CH3:40])=[O:41].[Cl:1][c:2]1[c:3](-[c:21]2[c:22]([F:29])[cH:23][c:24]([F:28])[cH:25][c:26]2[F:27])[c:4]([NH:14][CH:15]([C:16]([F:17])([F:18])[F:19])[CH3:20])[n:5][c:6](-[c:8]2[n:9][cH:10][cH:11][n:12][cH:13]2)[n:7]1.[H-:36].[Na+:37]>>[Cl:1][c:2]1[c:3](-[c:21]2[c:22]([F:29])[cH:23][c:24]([O:35][CH2:34][CH2:33][CH2:32][NH:31][CH3:30])[cH:25][c:26]2[F:27])[c:4]([NH:14][CH:15]([C:16]([F:17])([F:18])[F:19])[CH3:20])[n:5][c:6](-[c:8]2[n:9][cH:10][cH:11][n:12][cH:13]2)[n:7]1
