3-Amino-1,2-propanediol → N-(2,3-Di(acryloyloxy)propyl)hexahydrophthalimide

HRID 3070

Reaktionsgleichung

Reaktionsgleichung von HRID 3070
[NH2:1][CH2:2][CH:3]([OH:6])[CH2:4][OH:5].[C:7]1(=[O:17])[O:12][C:10](=O)[CH:9]2[CH2:13][CH2:14][CH2:15][CH2:16][CH:8]12>C(O)C>[C:10]([O:6][CH:3]([CH2:4][O:5][C:7](=[O:17])[CH:8]=[CH2:16])[CH2:2][N:1]1[C:7](=[O:17])[CH:8]2[CH2:16][CH2:15][CH2:14][CH2:13][CH:9]2[C:10]1=[O:12])(=[O:12])[CH:9]=[CH2:13]

Komponenten

4

Edukt 2

HCID 735613-Amino-1,2-propanediolHCID 85689Hexahydrophthalic anhydride

Produkt 1

HCID 18934212N-(2,3-Di(acryloyloxy)propyl)hexahydrophthalimideAusbeute 109,7 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

A 500-ml, two necked flask was equipped a magnetic stirring bar, heating mantle and condenser. The flask was charged with 46 g of 3-amino-1,2-propanediol (0.50 mol.) and 300 ml of ethanol. Next, 77 g of hexahydrophthalic anhydride (0.50 mol.) was slowly added to the flask after which the reaction was refluxed for 12 hours. The imide formation was confirmed by IR. The ethanol was removed by a rotoevaporator to yield 92 g (81%) of the N-[2,3-di(hydroxy)propyl]hexahydrophthalimide.

Aufarbeitung

  1. customA 500-ml, two necked flask was equipped a magnetic stirring bar
  2. temperatureheating mantle and condenser
  3. temperaturewas refluxed for 12 hours
  4. customThe ethanol was removed by a rotoevaporator

Quellen und Nachweise

ORD-Eintrag
ord-ebb2fd6722bb446b8b566d5f8733e3f7
Quelldatensatz
uspto-grants-1998_03
Patentnummer
US05733648

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