3-Aminopropan-1,2-diol

3-Amino-1,2-propanediol

HCID 73561CAS 616-30-8
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Grundinformationen

Standard-SMILES
NCC(O)CO
InChIKey
KQIGMPWTAHJUMN-UHFFFAOYSA-N
Summenformel
C3H9NO2
Durchschnittliche Molmasse
91,11 g/mol
Monoisotopische Masse
91,06332853

Überblick

structure given in first source; RN given refers to parent cpd

Namen und Bezeichner

Bevorzugter Name
3-Amino-1,2-propanediol
IUPAC
3-aminopropane-1,2-diol
Lokaler Name
3-Aminopropan-1,2-diol
Englischer Name
3-Amino-1,2-propanediol
Summenformel
C3H9NO2
Molmasse
91.11

Namen und Synonyme

3-Amino-1,2-propanediol616-30-81-Aminoglycerol1,2-Propanediol, 3-amino-2,3-Dihydroxypropylamine1-AminopropanediolRH369P864XNSC-67381DTXSID30862294RefChem:92848DTXCID90811081210-475-8
Weitere Namen anzeigen
APD3-amino-1,2-propanediol (APD)3--1,2-
Aminopropanediol3-Aminopropane-1,2-diol1-Amino-2,3-propanediol2,3-Propandiol-1-amine3-Amino-1,2-propandiolisoserinolMFCD00008140(S)-(-)-3-Amino-1,2-propanediol

Datenbank-Bezeichner

CAS
616-30-8
PubChem CID
73561
DTXSID
DTXSID30862294
UNII
RH369P864X
EC Number
210-475-8
Nikkaji
J1.661F

Eigenschaften

Berechnete Struktureigenschaften

XLogP
-2
Polarare Oberfläche (TPSA)
66,5 Ų
H-Brücken-Donoren
3
H-Brücken-Akzeptoren
3
Frei drehbare Bindungen
2
Schwere Atome
6

Experimentelle und physikochemische Eigenschaften

Food Contact SubstancesFCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR

Physikochemische Eigenschaften

Schmelzpunkt
55 · 55-57 °C
Siedepunkt
264 · 264-265 °C739 mm Hg(lit.)
Dichte
1.175 g/mL · 1.175 g/mL at 25 °C(lit.)
Dampfdruck
1 hPa · <1 hPa (20 °C)
Brechungsindex
20 · n20/D 1.492(lit.)
Flammpunkt
230 °F · >230 °F

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 4 Einträge

Danger

H314 (94%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]

P260, P264, P264+P265, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P317, P321, P363, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 184 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Gefahrenhinweise

Regulatory Information · 3 Einträge

Chemical: 1,2-Propanediol, 3-amino-

Status: Active Update: 21-02-2023 https://echa.europa.eu/registration-dossier/-/registered-dossier/5186

1,2-Propanediol, 3-amino-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.

Hazard Classes and CategoriesSkin Corr. 1B (94%)

Sicherheitsdaten

F
10-21
wgk
2
tsca
TSCA listed
ridadr
UN 2735 8/PG 2
hs_code
29221980
RTECS-Nr.
TY2800000

Chemie und Industrie

Verwendung und Herstellung

General Manufacturing Information1,2-Propanediol, 3-amino-: ACTIVE
Anwendungen · 3 Einträge

Beschreibung3-Amino-1,2-propanediol (APD) is a calcium metabolism regulator useful in the treatment of Paget's disease, tumor-induced hypercalcemia and other bone disorders involving increased osteoclastic activity.

Verwenden3-Amino-1,2-propanediol is used in the preparation of iohexol, which is a X-CT non-ionic contrast medium. It acts as a starting material in the production of specialty materials.

VerwendenA chiral glycerol derivative, namely 3-amino-1,2-propanediol, was employed for as the hydrogen bond donor (HBD) in the design of a new deep eutectic solvent (DES) with choline chloride acting as the hydrogen bond acceptor (HBA). The novel mixture was characterized and unambiguously classified as a DES[4].

Darstellung

synthetische3-Amino-1,2-propanediol is synthesized by reacting 3-chloro-1,2-propanediol (CPD) with ammonia in alkaline environment by adding sodium hydroxide. Afterwards, the product undergoes a series of purification steps.

Vor- und nachgelagerte Produkte

Anbieter50 Anbieter

国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
衢州润东化工有限公司0570-8789886 18892685668 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
INTATRADE GmbH+49 3493/605464 · [email protected]

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