Methanesulfonyl chloride → HCID 22009822, Verbindung
Reaktionsgleichung
[C:1]1(/[CH:7]=[CH:8]/[C:9]2[O:10][CH:11]=[C:12]([CH2:14][O:15][C:16]3[CH:21]=[CH:20][C:19]([CH2:22][CH2:23][OH:24])=[CH:18][CH:17]=3)[N:13]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:25][S:26](Cl)(=[O:28])=[O:27]>>[CH3:25][S:26]([O:24][CH2:23][CH2:22][C:19]1[CH:18]=[CH:17][C:16]([O:15][CH2:14][C:12]2[N:13]=[C:9](/[CH:8]=[CH:7]/[C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)[O:10][CH:11]=2)=[CH:21][CH:20]=1)(=[O:28])=[O:27]Komponenten
3
Versuchsvorschrift
In substantially the same manner as in Reference Example 12, 2-[4-[2-[(E)-2-phenylethenyl]-4-oxazolylmethoxy]phenyl]ethanol was allowed to react with methanesulfonyl chloride to give 2-[4-[2-[(E)-2-phenylethenyl]-4-oxazolylmethoxy]phenyl]ethyl methanesulfonate. The yield was 82%. Recrystallization from acetone-isopropyl ether gave colorless prisms, mp 121-122° C.
Quellen und Nachweise
- ORD-Eintrag
- ord-b5935426da784f47a9c6d488000669d9
- Quelldatensatz
- uspto-grants-2001_04