Hydrazine hydrate (1:1) → N5-[2-[[[5-(Dimethylamino)methyl-2-furanyl]methyl]thio]ethyl]-1H-1,2,4-triazole-3,5-diamine
Reaktionsgleichung
[OH2:1].[NH2:2][NH2:3].[C:4]([NH:6][C:7](SC)=[N:8][CH2:9][CH2:10][S:11][CH2:12][C:13]1O[C:15]([CH2:18][N:19]([CH3:21])[CH3:20])=[CH:16][CH:17]=1)#[N:5]>C(O)C>[CH3:20][N:19]([CH2:18][C:15]1[O:1][C:13]([CH2:12][S:11][CH2:10][CH2:9][NH:8][C:7]2[NH:3][N:2]=[C:4]([NH2:5])[N:6]=2)=[CH:17][CH:16]=1)[CH3:21]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
Hydrazine hydrate (3.5 ml) was added to a solution of N-cyano-N'-[2-[[[5-(dimethylamino)methyl-2-furanyl]methyl]thio]ethyl]carbamimidothioic acid, methyl ester (5.47 g) in ethanol (40 ml). After stirring for 3 days at room temperature the solvent was removed and the residual oil crystallised from water to give the title compound as white needles (2.95 g) m.p. 76°-78.5°.