6-Hydroxymethylquinoline → 6-Quinolinecarbaldehyde

HRID 326250

Reaktionsgleichung

Reaktionsgleichung von HRID 326250
[N:1]1[C:10]2[C:5](=[CH:6][C:7]([CH2:11][OH:12])=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1>[O-2].[Mn+4].[O-2].ClC(Cl)Cl>[N:1]1[C:10]2[C:5](=[CH:6][C:7]([CH:11]=[O:12])=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1

Komponenten

4

Edukt 1

HCID 15143856-Hydroxymethylquinoline

Produkt 1

HCID 7656536-QuinolinecarbaldehydeAusbeute 82,7 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 178418406HCID 178418406, VerbindungKatalysatorHCID 6212ChloroformLösungsmittel

Versuchsvorschrift

A mixture of 34 parts of 6-quinolinemethanol, 70 parts of manganese(IV)oxide and 300 parts of trichloromethane was stirred for 24 hours at room temperature. The reaction mixture was filtered over diatomaceous earth and the filtrate was evaporated, yielding 27.7 parts (82.7%) of 6-quinolinecarboxaldehyde; mp. 72° C. (interm. 16).

Aufarbeitung

  1. filtrationThe reaction mixture was filtered over diatomaceous earth
  2. customthe filtrate was evaporated

Quellen und Nachweise

ORD-Eintrag
ord-f0636ddc50f9408ab8832b5a92269345
Quelldatensatz
uspto-grants-1993_12
Patentnummer
US05268380

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