Acetic Anhydride → 5-(Trifluoromethyl)isobenzofuran-1,3-dione
Reaktionsgleichung
[F:1][C:2]([F:16])([F:15])[C:3]1[CH:4]=[C:5]([C:12]([OH:14])=[O:13])[C:6](=[CH:10][CH:11]=1)[C:7](O)=[O:8].C(OC(=O)C)(=O)C>>[F:1][C:2]([F:16])([F:15])[C:3]1[CH:4]=[C:5]2[C:12](=[O:14])[O:13][C:7](=[O:8])[C:6]2=[CH:10][CH:11]=1Komponenten
3
Versuchsvorschrift
4-Trifluoromethyl-phthalic acid (106.6 g.) and acetic anhydride (215 cc.) are heated to the reflux temperature for 30 minutes. After concentration under reduced pressure (30 mm Hg), the residue is stirred with cyclohexane (420 cc.). After filtration and drying, 4-trifluoromethyl-phthalic anhydride (73.5 g.) melting at 54° C is obtained.
Aufarbeitung
- concentrationAfter concentration under reduced pressure (30 mm Hg)
- filtrationAfter filtration
- customdrying
Quellen und Nachweise
- ORD-Eintrag
- ord-6eae555cb5c84c91b3e011b3515d54ee
- Quelldatensatz
- uspto-grants-1977_04
- Patentnummer
- US04016274
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