2-Chloroethanol → Biphenol-diethanol

HRID 329346

Reaktionsgleichung

Reaktionsgleichung von HRID 329346
[C:1]1([OH:14])[C:2]([C:7]2[C:8]([OH:13])=[CH:9][CH:10]=[CH:11][CH:12]=2)=[CH:3][CH:4]=[CH:5][CH:6]=1.[OH-].[Na+].Cl[CH2:18][CH2:19][OH:20].[CH2:21]([OH:23])[CH3:22]>>[C:8]1([OH:13])[C:7]([C:2]2[C:1]([OH:14])=[CH:6][CH:5]=[CH:4][CH:3]=2)=[C:12]([CH2:22][CH2:21][OH:23])[C:11]([CH2:18][CH2:19][OH:20])=[CH:10][CH:9]=1

Komponenten

5

Edukt 4

HCID 342-ChloroethanolHCID 702Ethanol2×HCID 14798Sodium HydroxideHCID 15731(1,1'-Biphenyl)-2,2'-diol

Produkt 1

HCID 19996287Biphenol-diethanol

Versuchsvorschrift

To biphenol (0.5 mole) and 200 milliliters of absolute ethanol and sodium hydroxide (1.1 millimole) at 80° C. was added dropwise a solution of 2-chloroethanol (1 mole) in 50 milliliters of absolute ethanol. The mixture was refluxed for 48 hours, and then filtered hot and washed twice with boiling ethanol (100 milliliters). Recrystallization from boiling water provided the precursor product biphenol-diethanol, 80 to 85 percent yield of colorless crystals. The melting point for this product was 210 to 211° C.

Aufarbeitung

  1. temperatureThe mixture was refluxed for 48 hours
  2. filtrationfiltered hot
  3. washwashed twice with boiling ethanol (100 milliliters)
  4. customRecrystallization

Quellen und Nachweise

ORD-Eintrag
ord-3be03b6fed26496e874c1462685d7a91
Quelldatensatz
uspto-grants-1990_01
Patentnummer
US04891293

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