Benzyl Bromide → 1-(Phenylmethyl)pyrrolidine

HRID 329659

Reaktionsgleichung

Reaktionsgleichung von HRID 329659
[NH:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1.[CH2:6](Br)[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>CCOCC>[C:7]1([CH2:6][N:1]2[CH2:5][CH2:4][CH2:3][CH2:2]2)[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1

Komponenten

4

Edukt 2

HCID 7498Benzyl BromideHCID 31268Pyrrolidine

Produkt 1

HCID 1225011-(Phenylmethyl)pyrrolidine

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel

Versuchsvorschrift

A 25.0 ml portion of pyrrolidine was reacted with 10.9 ml of benzyl bromide in ether as described in Example 3, giving 12.3 g of 1-(phenylmethyl)pyrrolidine, which was then reacted with butyl lithium and diphenylphosphine chloride as described in Example 3, giving diphenyl]2-(1-pyrrolidinylmethyl)phenyl]phosphine.

Quellen und Nachweise

ORD-Eintrag
ord-9293d2e303a2441eba00c7ae2796c964
Quelldatensatz
uspto-grants-1990_01
Patentnummer
US04892885

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