Hydrochloric Acid → N-[(4,6-dimethylpyrimidin-2-yl)aminocarbonyl]-2-ethoxyaminocarbonylbenzenesulfonamide

HRID 329757

Reaktionsgleichung

Reaktionsgleichung von HRID 329757
C[Al](C)C.Cl.[CH2:6]([O:8][NH2:9])[CH3:7].[CH3:10][C:11]1[CH:16]=[C:15]([CH3:17])[N:14]=[C:13]([NH:18][C:19]([NH:21][S:22]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=2[C:31](OC)=[O:32])(=[O:24])=[O:23])=[O:20])[N:12]=1.Cl>C(Cl)Cl>[CH3:10][C:11]1[CH:16]=[C:15]([CH3:17])[N:14]=[C:13]([NH:18][C:19]([NH:21][S:22]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=2[C:31]([NH:9][O:8][CH2:6][CH3:7])=[O:32])(=[O:24])=[O:23])=[O:20])[N:12]=1

Komponenten

6

Edukt 4

HCID 313Hydrochloric AcidHCID 52997Sulfometuron-methylHCID 76850O-ethylhydroxylamine hydrochlorideHCID 16682925Trimethylaluminum

Produkt 1

HCID 19871558N-[(4,6-dimethylpyrimidin-2-yl)aminocarbonyl]-2-ethoxyaminocarbonylbenzenesulfonamide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

To 2.9 g of trimethylaluminum in 100 ml of methylene chloride is added 2.0 g of ethoxyamine hydrochloride with stirring at ambient temperature. To this mixture is added 3.0 g of N-[(4,6-dimethylpyrimidin-2-yl)aminocarbonyl]-2-methoxycarbonylbenzenesulfonamide and the solution is refluxed for 18 hours. The reaction mixture is treated with aqueous hydrochloric acid and the resulting precipitated product is purified by chromatography.

Aufarbeitung

  1. temperaturethe solution is refluxed for 18 hours
  2. customthe resulting precipitated product
  3. customis purified by chromatography

Quellen und Nachweise

ORD-Eintrag
ord-a3ef8abf81d14e7cb104d6a293d44aef
Quelldatensatz
uspto-grants-1990_01
Patentnummer
US04892946

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