Hydrochloric Acid → 1-(2-Hydroxy-4-tetradecylphenyl)-1-hexanone

HRID 329989Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 329989
C([O:8][C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[CH:10]=1)(=O)CCCCC.[Cl-].[Al+3].[Cl-].[Cl-].Cl>CCOCC>[OH:8][C:9]1[CH:10]=[C:11]([CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[CH:12]=[CH:13][C:14]=1[C:9](=[O:8])[CH2:10][CH2:11][CH2:12][CH2:13][CH3:14]

Komponenten

5

Edukt 3

HCID 313Hydrochloric AcidHCID 6451240Aluminum(III) ChlorideHCID 14819672HCID 14819672, Verbindung

Produkt 1

HCID 148196731-(2-Hydroxy-4-tetradecylphenyl)-1-hexanone

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel

Versuchsvorschrift

A 14.28 g portion of hexanoic acid, 3-tetradecylphenyl ester was heated to 90°-100° C., then 9.81 g of aluminum chloride was added in portions over 2 hours. Heating was continued for an additional hour, then the mixture was allowed to cool, diluted with ether and poured onto a mixture of ice and concentrated hydrochloric acid. The ether layer was washed with water, then dried and the solvent removed, giving 7 g of the desired compound, mp 44°-45° C.

Aufarbeitung

  1. temperatureHeating
  2. waitwas continued for an additional hour
  3. temperatureto cool
  4. washThe ether layer was washed with water
  5. customdried
  6. customthe solvent removed

Quellen und Nachweise

ORD-Eintrag
ord-a847de53c9ba4ec089d3cddeb4adf5c4
Quelldatensatz
uspto-grants-1990_01
Patentnummer
US04894367

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