Methanol → 2-Chloro-6-methoxypyridin-4-amine

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

To a solution of 1.84 g (44.0 mmol) sodium in 40 mL MeOH was added 6.72 g (40.0 mmol) 2,6-dichloro-pyridin-4-ylamine. The reaction mixture was stirred at 150° C. for 30 min under microwave irradiation. The solvent was evaporated and ice water was added. The precipitate was filtered off, washed with water and dried.

Herkunft & Nachweise