反应详情

温度

150 °C

To a solution of 1.84 g (44.0 mmol) sodium in 40 mL MeOH was added 6.72 g (40.0 mmol) 2,6-dichloro-pyridin-4-ylamine. The reaction mixture was stirred at 150° C. for 30 min under microwave irradiation. The solvent was evaporated and ice water was added. The precipitate was filtered off, washed with water and dried.

1. customThe solvent was evaporated
2. additionice water was added
3. filtrationThe precipitate was filtered off
4. washwashed with water
5. customdried