Oxalyl chloride → 2-Acetoxypropionyl Chloride

HRID 337005

Reaktionsgleichung

Reaktionsgleichung von HRID 337005
[C:1]([O:4][CH:5]([CH3:9])[C:6](O)=[O:7])(=[O:3])[CH3:2].C(Cl)(=O)C([Cl:13])=O>>[C:1]([O:4][CH:5]([CH3:9])[C:6]([Cl:13])=[O:7])(=[O:3])[CH3:2]

Komponenten

3

Edukt 2

HCID 65578Oxalyl chlorideHCID 790412-Acetoxypropionic Acid

Produkt 1

HCID 45474922-Acetoxypropionyl Chloride

Versuchsvorschrift

Stir a mixture of 2-acetoxy-propionic acid (550 g, 4.16 mol) in oxalyl chloride (500 mL) at room temperature for overnight. After removal of oxalyl chloride under vacuum, ˜700 g crude product is obtained (quantitative yield crude), which is used directly in the next step. 1H NMR (CDCl3, 400 MHz): δ 5.16 (m, 1H), 2.13 (s, 3H), 1.58 (d, J=7.2, 3H).

Aufarbeitung

  1. customAfter removal of oxalyl chloride under vacuum

Quellen und Nachweise

ORD-Eintrag
ord-97d476e5da9d4d159a05dfc490b1bddd
Quelldatensatz
uspto-grants-2014_11
Patentnummer
US08889710B2

Verknüpfte Notizen

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