Peracetic Acid → Quinoline 1-oxide

HRID 34262

Reaktionsgleichung

Reaktionsgleichung von HRID 34262
C(OO)(=[O:3])C.[N:6]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH:9]=[CH:8][CH:7]=1>>[N+:6]1([O-:3])[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH:9]=[CH:8][CH:7]=1

Komponenten

3

Edukt 2

HCID 6585Peracetic AcidHCID 7047Quinoline

Produkt 1

HCID 15366Quinoline 1-oxide

Versuchsvorschrift

Peracetic acid (7.5 mL, 39 mmole, 40%) and quinoline (5 g, 39 mmole) were stirred for 2 hours. Much of the acetic acid was removed from the reaction mixture in vacuo. The resulting residue was dissolved in methylene chloride (50 mL) and washed twice with saturated sodium bicarbonate solution. After drying over MgSO4 the solvent was evaporated and the residue was triturated with ether. The resulting tan solid was collected by filtration. This material was carried on without further characterization.

Aufarbeitung

  1. customMuch of the acetic acid was removed from the reaction mixture in vacuo
  2. dissolutionThe resulting residue was dissolved in methylene chloride (50 mL)
  3. washwashed twice with saturated sodium bicarbonate solution
  4. dry with materialAfter drying over MgSO4 the solvent
  5. customwas evaporated
  6. customthe residue was triturated with ether
  7. filtrationThe resulting tan solid was collected by filtration

Quellen und Nachweise

ORD-Eintrag
ord-fbb987f1da9849cb93d557b6a2157e9e
Quelldatensatz
uspto-grants-1988_08
Patentnummer
US04761403

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