12-Methoxydodecanoate → 12-Methoxydodecanoyl chloride

HRID 342721Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 342721
[C:1](Cl)(=O)[C:2]([Cl:4])=[O:3].[CH3:7][O:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18]CC(O)=O>C1(C)C=CC=CC=1>[CH3:7][O:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:1][C:2]([Cl:4])=[O:3]

Komponenten

4

Edukt 2

HCID 142012-MethoxydodecanoateHCID 65578Oxalyl chloride

Produkt 1

HCID 1961175912-Methoxydodecanoyl chlorideAusbeute 99,9 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel

Versuchsvorschrift

Oxalyl chloride (16.0 g, 70 mmol) was added dropwise to a solution of 12-methoxydodecanoic acid (9.8 g, 77 mmol) in 300 mL of anhydrous toluene. After stirring at room temperature for 16 hours the solvent was removed on a rotary evaporator. The residue was taken up in anhydrous toluene and concentrated to give the title compound (17.4 g) as a yellow liquid. The structure was verified by infrared spectroscopy (1796 cm-1) and NMR.

Aufarbeitung

  1. customwas removed on a rotary evaporator
  2. concentrationconcentrated

Quellen und Nachweise

ORD-Eintrag
ord-826b2a5b37604c488655ae23e4757607
Quelldatensatz
uspto-grants-1999_01
Patentnummer
US05859052

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