O-Cresol → HCID 54530810, Verbindung

HRID 342754

Reaktionsgleichung

Reaktionsgleichung von HRID 342754
[C:1]1([CH3:8])[C:6]([OH:7])=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:9]([OH:22])(=O)[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][C:18]([OH:20])=O>>[OH:7][C:6]1[CH:5]=[CH:4][C:3]([CH2:3][CH2:4][CH2:5][CH2:6][CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][C:12]2[CH:11]=[CH:10][C:9]([OH:22])=[C:1]([CH3:8])[CH:2]=2)=[CH:2][C:1]=1[CH3:8].[OH:7][C:6]1[CH:5]=[CH:4][C:3]([C:18](=[O:20])[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][C:9]([C:3]2[CH:4]=[CH:5][C:6]([OH:7])=[C:1]([CH3:8])[CH:2]=2)=[O:22])=[CH:2][C:1]=1[CH3:8]

Komponenten

4

Edukt 2

HCID 335O-CresolHCID 5192Sebacic Acid

Produkt 2

HCID 54530810HCID 54530810, VerbindungHCID 545710481,10-Bis(4-hydroxy-3-methylphenyl)decane-1,10-dione

Reaktionsbedingungen

Temperatur
80 °C

Versuchsvorschrift

This was prepared by the method reported by Schlack and Koller in Aromatic aliphatic diketones. P Schlack and W Koller. Ger. 1,086,711 Aug. 11, 1960. The title compound was prepare by treatment of orthocresol (2.2 moles) with sebacic acid (1 mole) in the presence of polyphosphoric acid (3 moles). The mixture was stirred for 4 hrs at 80° C. and poured to ice-water after cooling. The precipitant was filtered, dissolved in ethyl acetate and washed with water three times. The solvent was evaporated to yield a crude 1,10-bis(4-hydroxy-3-methylphenyl)decane-1,10-dione which was then subjected to Clemmensen reduction to give the title compound.

Aufarbeitung

  1. customThis was prepared by the method
  2. temperatureafter cooling
  3. filtrationThe precipitant was filtered
  4. dissolutiondissolved in ethyl acetate
  5. washwashed with water three times
  6. customThe solvent was evaporated

Quellen und Nachweise

ORD-Eintrag
ord-116a6e421b2e46a3bc83e2cbd8661c88
Quelldatensatz
uspto-grants-1999_01
Patentnummer
US05859067

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