HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(+/-)-5-(2,5-Dioxo-4-imidazolidinylmethyl)-3-(1-methyl-4-piperidyl)-1H-indole → (+/-)-3-[3-(1-Methyl-4-piperidyl)-1H-indol-5-yl]alanine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (+/-)-5-(2,5-Dioxo-4-imidazolidinylmethyl)-3-(1-methyl-4-piperidyl)-1H-indole | HCID 15233277 | — |
| Edukt | Barium hydroxide, monohydrate | HCID 17749100 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Produkt | (+/-)-3-[3-(1-Methyl-4-piperidyl)-1H-indol-5-yl]alanine | HCID 22852202 | — |
Reaktionsschritte
A solution of the product from step (d) (2.4 g) and barium hydroxide hydrate (8.4 g) in water (50 ml) was refluxed for 72 hours, then cooled and evaporated in vacuo. The residue was taken up in hot methanol and filtered to remove barium salts.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05863935 |
| Quelldatensatz | uspto-grants-1999_01 |
| ORD ID | ord-318bfde53829421087aea779f67bc012 |
| Quellennotiz | uspto-grants-1999_01 |