4-((Dimethylamino)methyl)benzonitrile → HCID 19993416, Verbindung

HRID 344994Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 344994
[CH:1]1[C:18]2[C:5](=[C:6]([C:19]3[CH:20]=[C:21]([CH:24]=[CH:25][CH:26]=3)[CH2:22][Br:23])[C:7]3[C:16]([CH:17]=2)=[CH:15][C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[CH:8]=3)[CH:4]=[CH:3][CH:2]=1.[CH3:27][N:28]([CH2:30][C:31]1[CH:36]=[CH:35][C:34]([C:37]#[N:38])=[CH:33][CH:32]=1)[CH3:29].[PH4+].[AsH4+]>C(#N)C.C(OCC)C>[Br-:23].[C:37]([C:34]1[CH:33]=[CH:32][C:31]([CH2:30][N+:28]([CH2:22][C:21]2[CH:24]=[CH:25][CH:26]=[C:19]([C:6]3[C:7]4[C:16](=[CH:15][C:14]5[C:9]([CH:8]=4)=[CH:10][CH:11]=[CH:12][CH:13]=5)[CH:17]=[C:18]4[C:5]=3[CH:4]=[CH:3][CH:2]=[CH:1]4)[CH:20]=2)([CH3:27])[CH3:29])=[CH:36][CH:35]=1)#[N:38]

Komponenten

7

Edukt 4

HCID 8263294-((Dimethylamino)methyl)benzonitrileHCID 5460504PhosphoniumHCID 5460506ArsoniumHCID 19993410HCID 19993410, Verbindung

Produkt 1

HCID 19993416HCID 19993416, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 3283Diethyl EtherLösungsmittelHCID 6342AcetonitrileLösungsmittel

Versuchsvorschrift

A mixture of (B) and N,N-dimethyl-4-cyanobenzylamine in acetonitrile was refluxed for 2 hr. The reaction mixture was then poured into diethyl ether, and the crude product was collected by filtration. The crude product was recrystallized from ethanol. The same reaction can be used to prepare the corresponding phosphonium and arsonium salts.

Aufarbeitung

  1. temperaturewas refluxed for 2 hr
  2. filtrationthe crude product was collected by filtration
  3. customThe crude product was recrystallized from ethanol
  4. customThe same reaction

Quellen und Nachweise

ORD-Eintrag
ord-170f77478cd344a1a077d6f87d7c2d30
Quelldatensatz
uspto-grants-1991_10
Patentnummer
US05055376

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