4-Methylmorpholine → (1R,2S)-ethyl 1-((3R,5S)-1-((S)-2-(tert-butoxycarbonyl)-3-(2-nitro-N-(pent-4-enyl)phenylsulfonamido)propanoyl)-3-(isoquinolin-1-yloxy)pyrrolidine-5-carboxamido)-2-vinylcyclopropanecarboxylate

Reaktionsgleichung

[C:1]([O:5][C:6]([C@@H:8]([CH2:12][N:13]([CH2:26][CH2:27][CH2:28][CH:29]=[CH2:30])[S:14]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[N+:23]([O-:25])=[O:24])(=[O:16])=[O:15])[C:9](O)=[O:10])=[O:7])([CH3:4])([CH3:3])[CH3:2].Cl.Cl.[CH2:33]([O:35][C:36]([C:38]1([NH:43][C:44]([CH:46]2[CH2:50][CH:49]([O:51][C:52]3[C:61]4[C:56](=[CH:57][CH:58]=[CH:59][CH:60]=4)[CH:55]=[CH:54][N:53]=3)[CH2:48][NH:47]2)=[O:45])[CH2:40][CH:39]1[CH:41]=[CH2:42])=[O:37])[CH3:34].CN1CCOCC1.CN(C(ON1N=NC2C=CC=NC1=2)=[N+](C)C)C.F[P-](F)(F)(F)(F)F>C(Cl)Cl.CCCCCC.C(OCC)(=O)C>[C:1]([O:5][C:6]([C@@H:8]([CH2:12][N:13]([CH2:26][CH2:27][CH2:28][CH:29]=[CH2:30])[S:14]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[N+:23]([O-:25])=[O:24])(=[O:16])=[O:15])[C:9]([N:47]1[C@H:46]([C:44]([NH:43][C@:38]2([C:36]([O:35][CH2:33][CH3:34])=[O:37])[CH2:40][C@H:39]2[CH:41]=[CH2:42])=[O:45])[CH2:50][C@@H:49]([O:51][C:52]2[C:61]3[C:56](=[CH:57][CH:58]=[CH:59][CH:60]=3)[CH:55]=[CH:54][N:53]=2)[CH2:48]1)=[O:10])=[O:7])([CH3:2])([CH3:4])[CH3:3]