HCID 21087563, Verbindung → HCID 21087564, Verbindung

HRID 348521Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 348521
[CH2:1]([N:3]1[C:15]2[CH:14]=[CH:13][C:12]([CH2:16][OH:17])=[CH:11][C:10]=2[C:9]2[C:4]1=[CH:5][CH:6]=[C:7]([O:18][CH3:19])[CH:8]=2)[CH3:2]>CC(C)=O.O=[Mn]=O>[CH2:1]([N:3]1[C:15]2[CH:14]=[CH:13][C:12]([CH:16]=[O:17])=[CH:11][C:10]=2[C:9]2[C:4]1=[CH:5][CH:6]=[C:7]([O:18][CH3:19])[CH:8]=2)[CH3:2]

Komponenten

4

Edukt 1

HCID 21087563HCID 21087563, Verbindung

Produkt 1

HCID 21087564HCID 21087564, VerbindungAusbeute 0,1 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 14801Manganese dioxideKatalysatorHCID 180AcetoneLösungsmittel

Versuchsvorschrift

A solution of 9-ethyl-3-hydroxymethyl-6-methoxycarbazole (0.305 g, 1.2 mmol) in acetone (5 mL) was treated with MnO2 (0.52 g, 6 mmol) and the reaction stirred at room temperature for 60 hours. The reaction mixture was filtered and the solvent evaporated under reduced pressure. The crude was purified by column chromatography (heptane/ethyl acetate 5/1) to afford 0.190 mg of the title compound.

Aufarbeitung

  1. filtrationThe reaction mixture was filtered
  2. customthe solvent evaporated under reduced pressure
  3. customThe crude was purified by column chromatography (heptane/ethyl acetate 5/1)

Quellen und Nachweise

ORD-Eintrag
ord-50a932ae424f4796823f5d18caf438eb
Quelldatensatz
uspto-grants-2007_02
Patentnummer
US07176322B2

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