Tert-butyl 4-benzylpiperazine-1-carboxylate → 1-Benzylpiperazine hydrochloride

HRID 352777

Reaktionsgleichung

Reaktionsgleichung von HRID 352777
[CH2:1]([N:8]1[CH2:13][CH2:12][N:11](C(OC(C)(C)C)=O)[CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[ClH:21].C(O)C>>[ClH:21].[CH2:1]([N:8]1[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Komponenten

3

Edukt 2

HCID 584330Tert-butyl 4-benzylpiperazine-1-carboxylateHCID 21887872Ethanol hydrochloride

Produkt 1

HCID 27566531-Benzylpiperazine hydrochlorideAusbeute 97 %

Versuchsvorschrift

To 1-benzyl-4-tert-butoxycarbonylpiperazine (3.12 g), saturated ethanol hydrochloride was added, followed by stirring for 90 minutes at room temperature. The solvent was distilled off under reduced pressure, followed by drying, whereby the title compound (2.73 g, 97%) was obtained as white powder.

Aufarbeitung

  1. distillationThe solvent was distilled off under reduced pressure
  2. customby drying

Quellen und Nachweise

ORD-Eintrag
ord-33705c0319e7456583203d04feae1405
Quelldatensatz
uspto-grants-2004_06
Patentnummer
US06747023B1

Verknüpfte Notizen

Wird geladen…