DL-Carnitine → Cyclohexyl acetyl carnitine chloride

HRID 35373

Reaktionsgleichung

Reaktionsgleichung von HRID 35373
[CH3:1][N+:2]([CH2:5][CH:6]([OH:11])[CH2:7][C:8]([O-:10])=[O:9])([CH3:4])[CH3:3].[CH:12]1(CC([Cl:21])=O)[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1.[CH2:22]([O:24]CC)[CH3:23]>FC(F)(F)C(O)=O>[CH:12]1([CH:5]([N+:2]([CH3:3])([CH3:4])[CH3:1])[C:6]([C:22](=[O:24])[CH3:23])([CH2:7][C:8](=[O:10])[O-:9])[OH:11])[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1.[Cl-:21]

Komponenten

5

Edukt 3

HCID 288DL-CarnitineHCID 3283Diethyl EtherHCID 2757989Cyclohexylacetyl chloride

Produkt 1

HCID 131715698Cyclohexyl acetyl carnitine chloride

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6422Trifluoroacetic acidLösungsmittel

Versuchsvorschrift

Carnitine chloride (2.97 g; 0.01 moles) was dissolved in trifluoro acetic acid (10 cc). To this solution was added cyclohexyl acetyl chloride (0.01 moles) prepared as previously disclosed and the resulting mixture was kept under stirring for 48 hours. Ethyl ether was then added and the resulting mixture was kept under stirring for 0.5 hours at 0° C. A precipitate was obtained, which was filtered off and dried under vacuum.

Aufarbeitung

  1. customprepared
  2. stirringunder stirring for 0.5 hours at 0° C
  3. customA precipitate was obtained
  4. filtrationwhich was filtered off
  5. customdried under vacuum

Quellen und Nachweise

ORD-Eintrag
ord-ccb56ca24b4b4916a6432cb595293d2a
Quelldatensatz
uspto-grants-1988_08
Patentnummer
US04766222

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