Pyridine → HCID 18936915, Verbindung
Reaktionsgleichung
[C:1]([O:4][C:5](=[O:7])[CH3:6])(=O)[CH3:2].OC1[C:10]([C:19]([NH2:21])=[O:20])=[CH:11][C:12]2[C:17](C=1)=[CH:16][CH:15]=[CH:14][CH:13]=2.N1C=CC=CC=1>>[C:5]([O:4][C:1]1[C:10]([C:19]([NH2:21])=[O:20])=[CH:11][C:12]2[C:17]([CH:2]=1)=[CH:16][CH:15]=[CH:14][CH:13]=2)(=[O:7])[CH3:6]Komponenten
4
Versuchsvorschrift
Acetic anhydride (19.2 ml, 200 mmol) was added to a solution of 18 (29.95 g, 160 mmol) in pyridine (32 ml, 400 mmol) and the mixture was maintained at room temperature for 30 minutes. The solid was filtered off, washed with acetone and dried (MgSO4), generating 27.06 g (74%) of 19 as pale yellow crystals, mp 201°-202° C. (lit. 203°-205° C.).
Aufarbeitung
- filtrationThe solid was filtered off
- washwashed with acetone
- dry with material