Water → HCID 54501552, Verbindung

HRID 357156Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 357156
C(O[CH:4]=[C:5]1[S:9][C:8](=[O:10])[NH:7][C:6]1=[O:11])C.[Na].[CH2:13]([SH:15])[CH3:14].O>C(O)C>[CH2:13]([S:15][CH:4]=[C:5]1[S:9][C:8](=[O:10])[NH:7][C:6]1=[O:11])[CH3:14]

Komponenten

5

Edukt 3

HCID 962WaterHCID 45051917Sodium ethanethiolHCID 537875085-(Ethoxymethylene)thiazolidine-2,4-dione

Produkt 1

HCID 54501552HCID 54501552, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

To a suspension of 5.20 g of 5-(ethoxymethylene)thiazolidine-2,4-dione (1:1.71 mixture with thiazolidine-2,4-dione, about 13.9 mmol) in 50 ml of ethanol, 5.0 g (59 mmol) of ethanethiol sodium salt was added at room temperature, followed by stirring under heating conditions for 3 hours. After cooling, the reaction mixture was poured into water and adjusted to a pH level of about 2. The resulting precipitate was collected by filtration, washed with water and then with n-hexane/diethyl ether and dried to yield 1.38 g (52.0%, light yellow powder) of the desired product.

Aufarbeitung

  1. additionwas added at room temperature
  2. temperatureAfter cooling
  3. filtrationThe resulting precipitate was collected by filtration
  4. washwashed with water
  5. dry with materialwith n-hexane/diethyl ether and dried

Quellen und Nachweise

ORD-Eintrag
ord-f2c262a790024d35b3922934d789170b
Quelldatensatz
uspto-grants-1998_11
Patentnummer
US05840732

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