Hydrochloric Acid → 2,3,4,5-Tetrafluorobenzoyl chloride

HRID 357695

Reaktionsgleichung

Reaktionsgleichung von HRID 357695
[F:1][C:2]1[C:7]([F:8])=[C:6]([F:9])[C:5]([F:10])=[CH:4][C:3]=1[C:11]([Cl:14])(Cl)Cl.[C]=[O:16].Cl>[Fe](Cl)(Cl)Cl.C(O)=O>[F:1][C:2]1[C:7]([F:8])=[C:6]([F:9])[C:5]([F:10])=[CH:4][C:3]=1[C:11]([Cl:14])=[O:16]

Komponenten

6

Edukt 3

HCID 313Hydrochloric AcidHCID 153460071,2,3,4-Tetrafluoro-5-(trichloromethyl)benzeneHCID 178418416HCID 178418416, Verbindung

Produkt 1

HCID 27336892,3,4,5-Tetrafluorobenzoyl chloride

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 24380Iron chloride (FeCl3)KatalysatorHCID 284Formic AcidLösungsmittel

Versuchsvorschrift

268 g of 2,3,4,5-tetrafluorobenzotrichloride were placed in a stirred apparatus and 5.3 [lacuna] of iron(III) chloride were added, 45 g of formic acid (98-100%) were pumped in over 8 hours at 60° C. Vigorous gas development (carbon monoxide, hydrogen chloride) began immediately. The gas stream was fed to an absorption tower via a cooler. After addition was complete, the mixture was stirred until the end of gas development. The product was then distilled. 195 g of 2,3,4,5-tetrafluorobenzoyl chloride were obtained (91.5% of theory); b.p.: 70°-72° C./20 mbar, nD25 : 1.4773.

Aufarbeitung

  1. additionwere added
  2. customwere pumped in over 8 hours at 60° C
  3. additionAfter addition
  4. distillationThe product was then distilled

Quellen und Nachweise

ORD-Eintrag
ord-7903e75866d04d5fb98f14728c9684aa
Quelldatensatz
uspto-grants-1998_11
Patentnummer
US05840975

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