Acetone Cyanohydrin → 2-((4-Hydroxybutyl)amino)-2-methylpropanenitrile

HRID 35945

Reaktionsgleichung

Reaktionsgleichung von HRID 35945
[CH3:1][C:2]([CH3:6])(O)[C:3]#[N:4].[NH2:7][CH2:8][CH2:9][CH2:10][CH2:11][OH:12]>C(Cl)Cl>[OH:12][CH2:11][CH2:10][CH2:9][CH2:8][NH:7][C:2]([CH3:6])([CH3:1])[C:3]#[N:4]

Komponenten

4

Edukt 2

HCID 6406Acetone CyanohydrinHCID 258684-Amino-1-butanol

Produkt 1

HCID 155119612-((4-Hydroxybutyl)amino)-2-methylpropanenitrile

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Reaktionsbedingungen

Temperatur
20 °C

Versuchsvorschrift

220 μl of acetone cyanohydrin and 200 μl of 4-amino 1-butanol were mixed together with stirring for 16 hours at 20° C. and then was diluted with 2 ml of methylene chloride, dried, filtered and the filtrate was concentrated under reduced pressure to obtain the propanonitrile which was used as is for the following stage.

Aufarbeitung

  1. customdried
  2. filtrationfiltered
  3. concentrationthe filtrate was concentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-af507ea0ea16417b8b65e6f6abd9ae52
Quelldatensatz
uspto-grants-1995_05
Patentnummer
US05411981

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