m-Chloroperbenzoic acid → Ethyl 2-butyl-1-[[2'-carboxy-(1,1'-biphenyl)-4-yl]-methyl]-4-(methylsulphinyl)-1H-imidazole-5-carboxylate

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	m-Chloroperbenzoic acid	HCID 70297	—
Edukt	Ethyl 2-butyl-1-[[2'-(methoxycarbonyl)-(1,1'-biphenyl)-4-yl]-methyl]-4-(methylthio)-1H-imidazole-5-carboxylate	HCID 21479063	—
Produkt	Ethyl 2-butyl-1-[[2'-carboxy-(1,1'-biphenyl)-4-yl]-methyl]-4-(methylsulphinyl)-1H-imidazole-5-carboxylate	HCID 21479009	259,4%

Reaktionsschritte

The operation is carried out as in Example 15 starting with 1.55 g of the product obtained in Example 21 using 213 mg of metachloroperbenzoic acid. 1.8 g of crude product is obtained which is chromatographed on silica (eluant: methylene chloride--acetone (7-3)). 1.5 g of desired product is obtained.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US05412101
Quelldatensatz	uspto-grants-1995_05
ORD ID	ord-e2c018c9a5bd4269b7945054007d746c
Quellennotiz	uspto-grants-1995_05